A Vinewood-area neighborhood — mid-rise residential along Figueroa Street and the Vinewood Boulevard corridor.
A Rockford Hills sub-neighborhood — the boutique-shopping-and-restaurants register adjacent to the wealthier residential zones.
GTA V's south-Los Santos neighborhood — Crenshaw / South-Central-coded working-class geography that anchors Franklin Clinton's origin storyline and overlaps with Ballas territorial presence.
GTA V's coastal neighborhood adjacent to Vespucci Beach on Los Santos's western coast — home to the Del Perro Pier and its Ferris wheel, anchoring one of the franchise's most-recognized beachfront landmark images.
A Vinewood-area neighborhood — boutique storefronts and mid-rise residential, the Melrose-coded part of Vinewood's footprint.
A downtown Los Santos public square — a recurring open-space landmark in V's early-game footage.
An East-Vinewood-area neighborhood — gentrifying mid-century residential around a small lake.
Downtown Los Santos's eastside neighborhood — home to the Mission Row Police Station, frequently encountered during wanted-level escalations.
GTA V's downtown financial-district neighborhood — skyscraper-density geography hosting Maze Bank Tower, FIB Headquarters, and IAA Headquarters, structurally analogous to Downtown LA / Bunker Hill in real-world Los Angeles.
A Rockford Hills sub-neighborhood — gated mansions and the high-end residential register that frames V's wealthy-character storylines.
GTA V's Beverly Hills analog — the high-end residential neighborhood of central Los Santos, home to Michael De Santa's mansion and the Vangelico jewelry store from V's first major heist.
GTA V's south-Los Santos neighborhood — South-Central-coded working-class geography adjacent to Davis and Chamberlain Hills, home to the Vanilla Unicorn strip club Trevor Philips acquires in V's middle act.
Downtown Los Santos's south-side garment-district analog — wholesale storefronts, parking structures, and dense urban grid.
GTA V's Venice Beach analog — the beachfront / boardwalk neighborhood of western Los Santos, anchoring V's coastal-leisure tonal register and one of the franchise's most-recognized beach-coded geographies.
GTA V's Hollywood analog — the entertainment-district neighborhood of central Los Santos, anchored by the Vinewood Sign on the Vinewood Hills, home to V's film-and-television-industry satire.
GTA V's mountain-side mansion district above Vinewood — Hollywood Hills-coded residential geography with winding streets, hillside properties, and panoramic views over central Los Santos. Distinct from Rockford Hills's lower-elevation Beverly Hills register.